Annotation Detail

Information
Associated Genes
AFF1
Associated Variants
AFF1 MUTATION
AFF1 MUTATION
Associated Disease
Memory impairment
Source Database
DisGeNET
Description
Active vaccination with AFF 1 resulted in decreased accumulation of α-syn oligomers in axons and synapses, accompanied by reduced degeneration of TH fibers in the caudo-putamen nucleus and by improvements in motor and memory deficits in both in vivo models.
Pubmed
24525765
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
8
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000271441872080303
Drugs