Annotation Detail
Information
- Associated Genes
- AFF1
- Associated Variants
-
AFF1 MUTATION
AFF1 MUTATION - Associated Disease
- Memory impairment
- Source Database
- DisGeNET
- Description
- Active vaccination with AFF 1 resulted in decreased accumulation of α-syn oligomers in axons and synapses, accompanied by reduced degeneration of TH fibers in the caudo-putamen nucleus and by improvements in motor and memory deficits in both in vivo models.
- Pubmed
- 24525765
- Section of the abstract supporting the evidence
- ALL_TEXT_3/3
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 8
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000271441872080303
Drugs