Annotation Detail
Information
- Associated Genes
- PITX1
- Associated Variants
-
PITX1 MUTATION
PITX1 MUTATION - Associated Disease
- Astrocytoma
- Source Database
- DisGeNET
- Description
- Herein we showed that activation of CD47 in human astrocytoma cell lines U87 and CCF- STTG1 (Grade IV), up-regulated the expression of UHRF1 with subsequent down-regulation of p16(INK4A), thus promoting cell proliferation.
- Pubmed
- 25550546
- Section of the abstract supporting the evidence
- ALL_TEXT_2/3
- Number of the section of the abstract supporting the evidence
- 2
- Number of the sentence supporting the evidence
- 6
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00162865123248182
Drugs