Annotation Detail

Information
Associated Genes
NRAS
Associated Variants
NRAS Q61
NRAS Q61
Associated Disease
melanoma
Source Database
CIViC Evidence
Description
Melanoma associated with NRAS Q61 mutation was more often associated with those at the extremity than those at the trunk.
Variant Origin
somatic
Variant Origin
Somatic
Evidence URL
https://civic.genome.wustl.edu/links/evidence_items/10
Gene URL
https://civic.genome.wustl.edu/links/genes/36
Variant URL
https://civic.genome.wustl.edu/links/variants/94
Rating
3
Evidence Type
Diagnostic
Disease
Melanoma
Evidence Direction
Supports
Evidence Level
B
Clinical Significance
Positive
Pubmed
23861977
Drugs