Annotation Detail

Information
Associated Genes
ACVRL1
Associated Variants
ACVRL1 p.Asp254del (p.D254del) ( ENST00000552678.2, ENST00000547400.6, ENST00000713619.1, ENST00000550683.5, ENST00000388922.9, ENST00000419526.6, ENST00000551576.6 )
ACVRL1 p.Asp254del (p.D254del) ( ENST00000388922.9, ENST00000419526.6, ENST00000547400.6, ENST00000550683.5, ENST00000551576.6, ENST00000552678.2, ENST00000713619.1 )
Associated Disease
Telangiectasia, hereditary hemorrhagic, type 2
Source Database
ClinVar
Description
NM_000020.3(ACVRL1):c.760_762del (p.Asp254del) AND Telangiectasia, hereditary hemorrhagic, type 2
ClinVar Allele ID
23289
ClinVar RefSeq Alternation Syntax
NM_001077401.2:c.760_762del
ClinVar RefSeq Alternation Syntax
NM_000020.3:c.760_762del
Clinical Significance Description
Pathogenic
Clinical Significance Last Update
2023-10-13
Clinical Significance Review Status
criteria provided, single submitter
URL
https://www.ncbi.nlm.nih.gov/clinvar/RCV000008735
ClinVar Disease
Telangiectasia, hereditary hemorrhagic, type 2
Observed Origin Sample
germline
Pubmed
11484689
Drugs