Annotation Detail

Information
Associated Genes
ERCC2
Associated Variants
ERCC2 p.Leu461Val (p.L461V) ( ENST00000391944.8, ENST00000391945.10, ENST00000684407.1 )
ERCC2 p.Leu461Val (p.L461V) ( ENST00000391944.8, ENST00000391945.10, ENST00000684407.1 )
Associated Disease
Trichothiodystrophy 1, photosensitive
Source Database
ClinVar
Description
NM_000400.4(ERCC2):c.1381C>G (p.Leu461Val) AND Trichothiodystrophy 1, photosensitive
ClinVar Allele ID
31818
ClinVar RefSeq Alternation Syntax
NM_000400.4:c.1381C>G
Clinical Significance Description
no classifications from unflagged records
Clinical Significance Last Update
2023-10-18
Clinical Significance Review Status
no classifications from unflagged records
URL
https://www.ncbi.nlm.nih.gov/clinvar/RCV000171546
ClinVar Disease
Trichothiodystrophy 1, photosensitive
Observed Origin Sample
germline
Pubmed
8571952
Pubmed
9195225
Pubmed
7849702
Drugs