Annotation Detail

Information
Associated Genes
CAV3
Associated Variants
CAV3 p.Pro105Leu (p.P105L) ( ENST00000343849.3, ENST00000397368.2 )
CAV3 p.Pro105Leu (p.P105L) ( ENST00000343849.3, ENST00000397368.2 )
Associated Disease
Muscular Dystrophies, Limb-Girdle
Source Database
DisGeNET
Description
Here, we explored the functional consequences of a Cav-3 mutation (P104L) inducing the 1C type limb-girdle muscular dystrophy (LGMD 1C) in human on intracellular Ca(2+) regulation of adult skeletal muscle fibres.
Pubmed
18509671
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.251139048276957
Year of publication
2008
Drugs