Annotation Detail

Information
Associated Genes
IAPP
Associated Variants
IAPP MUTATION
IAPP MUTATION
Associated Disease
Diabetes
Source Database
DisGeNET
Description
We report that a deficit in UCHL1 accelerated the onset of diabetes in hIAPP transgenic mice, due to a decrease in β-cell mass caused by increased β-cell apoptosis.
Pubmed
24879150
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
5
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00434306995328485
Drugs