Annotation Detail
Information
- Associated Genes
- KL
- Associated Variants
-
KL MUTATION
KL MUTATION - Associated Disease
- diabetes mellitus
- Source Database
- DisGeNET
- Description
- Klotho expression was suppressed in the diabetic rats, but was increased by rAAV.mKL delivery. rAAV.mKL significantly suppressed diabetes-induced renal hypertrophy and histopathological changes, reduced renal collagen fiber generation and decreased kidney hypertrophy index.
- Pubmed
- 25695625
- Section of the abstract supporting the evidence
- ALL_TEXT_3/3
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 8
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000542883744160607
Drugs