Annotation Detail

Information
Associated Genes
ERCC2
Associated Variants
ERCC2 p.Leu461Val (p.L461V) ( ENST00000391944.8, ENST00000391945.10, ENST00000684407.1 )
ERCC2 p.Leu461Val (p.L461V) ( ENST00000391944.8, ENST00000391945.10, ENST00000684407.1 )
Associated Disease
Xeroderma Pigmentosum, Complementation Group D
Source Database
DisGeNET
Description
In cell line GM436 a C-->G transversion was found at nucleotide position 1411 in the XPD (ERCC2) cDNA, a change expected to result in a Leu461Val substitution.
Pubmed
7849702
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.565428837441606
Year of publication
1994
Drugs