Annotation Detail

Information
Associated Genes
ERCC2
Associated Variants
ERCC2 p.Ser541Arg (p.S541R) ( ENST00000391944.8, ENST00000391945.10, ENST00000684407.1 )
ERCC2 p.Ser541Arg (p.S541R) ( ENST00000391944.8, ENST00000391945.10, ENST00000684407.1 )
Associated Disease
Xeroderma Pigmentosum, Complementation Group D
Source Database
DisGeNET
Description
Here we report on two causative mutations of the XPD gene in XP61OS, a Japanese XP group D patient who has only mild skin symptoms of XP without CS, TTD, or other neurological complications.
Pubmed
9101292
Original source reporting the Gene Disease association
UNIPROT
DisGENET score for the Gene Disease association
0.565428837441606
Year of publication
1997
Drugs