Annotation Detail

Information
Associated Genes
IAPP
Associated Variants
IAPP MUTATION
IAPP MUTATION
Associated Disease
hyperglycemia
Source Database
DisGeNET
Description
Aggregation of human IAPP was associated with marked upregulation of proinflammatory gene expression in islets of obese hIAPP(Tg/0) mice, together with amyloid deposition and fasting hyperglycaemia.
Pubmed
25491100
Section of the abstract supporting the evidence
RESULTS
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
7
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00135720936040152
Drugs