Annotation Detail

Information
Associated Genes
ADH1B
Associated Variants
ADH1B p.His48Arg (p.H48R) ( ENST00000305046.13, ENST00000506651.5, ENST00000625860.2 )
ADH1B p.His48Arg (p.H48R) ( ENST00000305046.13, ENST00000506651.5, ENST00000625860.2 )
Associated Disease
Cancer of Head and Neck
Source Database
DisGeNET
Description
Multiple regression analyses showed that individuals with the mutant genotype ADH1B Arg(48)His who consume alcohol >30 g/L/day have more than four times the risk for HNC (OR = 4.42; 95% CI, 1.21-16.11).
Pubmed
19887496
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00399568321108385
Year of publication
2010
Drugs