Annotation Detail

Information
Associated Genes
APC
Associated Variants
APC p.Tyr935Ter (p.Y935*) ( ENST00000507379.6, ENST00000257430.9, ENST00000508376.6, ENST00000512211.7, ENST00000504915.3, ENST00000509732.6, ENST00000713638.1, ENST00000713639.1 )
APC p.Tyr935Ter (p.Y935*) ( ENST00000257430.9, ENST00000504915.3, ENST00000507379.6, ENST00000508376.6, ENST00000509732.6, ENST00000512211.7, ENST00000713638.1, ENST00000713639.1 )
APC p.Tyr935= (p.Y935=) ( ENST00000507379.6, ENST00000257430.9, ENST00000504915.3, ENST00000508376.6, ENST00000509732.6, ENST00000512211.7, ENST00000713638.1, ENST00000713639.1 )
APC p.Tyr935Ter (p.Y935*) ( ENST00000509732.6, ENST00000507379.6, ENST00000508376.6, ENST00000257430.9, ENST00000504915.3, ENST00000512211.7, ENST00000713638.1, ENST00000713639.1 )
APC p.Tyr935Ter (p.Y935*) ( ENST00000257430.9, ENST00000504915.3, ENST00000507379.6, ENST00000508376.6, ENST00000509732.6, ENST00000512211.7, ENST00000713638.1, ENST00000713639.1 )
APC p.Tyr935= (p.Y935=) ( ENST00000257430.9, ENST00000504915.3, ENST00000507379.6, ENST00000508376.6, ENST00000509732.6, ENST00000512211.7, ENST00000713638.1, ENST00000713639.1 )
Associated Disease
Adenomatous Polyposis Coli
Source Database
DisGeNET
Description
We identified a mutation in the APC gene that results in a truncated protein (Y935X) in the FAP proband, and subsequently in 12 FAP-affected members.
Pubmed
16292097
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.776808767486449
Year of publication
2005
Drugs