Annotation Detail
Information
- Associated Genes
- AKT3
- Associated Variants
-
AKT3 MUTATION
AKT3 MUTATION - Associated Disease
- melanoma
- Source Database
- DisGeNET
- Description
- Nevertheless, most melanomas carried additional oncogenic mutations at baseline (for example, RAC1 and AKT3) that activate the MAPK and PI3K pathways and are thus predicted to diminish response to MAPK inhibitors.
- Pubmed
- 25452114
- Section of the abstract supporting the evidence
- ALL_TEXT_3/3
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 7
- Original source reporting the Gene Disease association
- BeFree,LHGDN
- DisGENET score for the Gene Disease association
- 0.0106160275761242
Drugs