Annotation Detail

Information
Associated Genes
IGF1R
Associated Variants
IGF1R MUTATION
IGF1R MUTATION
Associated Disease
multiple myeloma
Source Database
DisGeNET
Description
Our study suggests that combination treatment with AZD8055 and IGF1R-blocking agents is a promising strategy in multiple myeloma with potential IGF1R/Akt signaling-mediated survival.
Pubmed
25172964
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
10
Original source reporting the Gene Disease association
BeFree,GAD
DisGENET score for the Gene Disease association
0.00581983144552528
Drugs