Annotation Detail

Information
Associated Genes
STAT4
Associated Variants
STAT4 MUTATION
STAT4 MUTATION
Associated Disease
mycosis fungoides
Source Database
DisGeNET
Description
In summary, our results suggest that loss of STAT4 expression and associated switch to Th2 phenotype during Mycosis Fungoides progression may be driven via aberrant histone acetylation and/or upregulation of oncogenic miR-155 microRNA.
Pubmed
25486484
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
10
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000542883744160607
Drugs