Annotation Detail

Information
Associated Genes
DMPK
Associated Variants
DMPK MUTATION
DMPK MUTATION
Associated Disease
Myotonic dystrophy
Source Database
DisGeNET
Description
Expandable (CTG)n repeats in the 3' UTR of the DMPK gene are a cause of myotonic dystrophy type 1 (DM1), which leads to a toxic RNA gain-of-function disease.
Pubmed
24824895
Section of the abstract supporting the evidence
ALL_TEXT_1/3
Number of the section of the abstract supporting the evidence
1
Number of the sentence supporting the evidence
1
Original source reporting the Gene Disease association
BeFree,CLINVAR,CTD_human,GAD,LHGDN,MGD
DisGENET score for the Gene Disease association
0.44470979263307
Drugs