Annotation Detail

Information
Associated Genes
P2RX7
Associated Variants
P2RX7 MUTATION
P2RX7 MUTATION
Associated Disease
Neoplasm Metastasis
Source Database
DisGeNET
Description
These data indicate that P2X7 stimulates cell invasion and metastasis in prostate cancer cells via some EMT/invasion-related genes, as well as PI3K/AKT and ERK1/2 signaling pathways.
Pubmed
25486274
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
7
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000542883744160607
Drugs