Annotation Detail

Information
Associated Genes
ATAT1
Associated Variants
CRHR1 c.435-99G>A, LINC02210-CRHR1 c.-92+141G>A ( ENST00000352855.9, ENST00000580876.6, ENST00000398285.7, ENST00000634540.1, ENST00000577353.5, ENST00000314537.10 )
CRHR1 c.435-99G>A, LINC02210-CRHR1 c.-92+141G>A ( ENST00000314537.10, ENST00000352855.9, ENST00000398285.7, ENST00000577353.5, ENST00000580876.6, ENST00000634540.1 )
Associated Disease
Depressive Symptoms
Source Database
DisGeNET
Description
Specifically, we found that the impact of childhood maltreatment on adult depressive symptoms was significantly higher in individuals (i) with two copies of the CRHR1 TAT haplotype, and (ii) homozygous for the G allele of rs17689882.
Pubmed
22748421
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000271441872080303
Year of publication
2012
Drugs