Annotation Detail
Information
- Associated Genes
- SLC6A3
- Associated Variants
-
SLC6A3 MUTATION
SLC6A3 MUTATION - Associated Disease
- Parkinson disease
- Source Database
- DisGeNET
- Description
- Rs1109303 (T>G) variant within the INPP5K gene on chromosome 17p13.3 demonstrated a genome-wide significant interaction with serum urate level to predict striatal dopamine transporter density among all PPMI participants (n = 359) with possible PD (p = 2.01 × 10(-8) ; after excluding participants with SWEDD [scan without evidence of dopaminergic deficit]: p = 1.12 × 10(-9) ; n = 316).
- Pubmed
- 26284320
- Section of the abstract supporting the evidence
- RESULTS
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 8
- Original source reporting the Gene Disease association
- BeFree,CTD_human,GAD,LHGDN
- DisGENET score for the Gene Disease association
- 0.162940149660312
Drugs