Annotation Detail

Information
Associated Genes
RIGI
Associated Variants
RIGI MUTATION
RIGI MUTATION
Associated Disease
Respiratory Syncytial Virus Infections
Source Database
DisGeNET
Description
Here, we show that RSV infection of lung epithelial cells induces expression of RIG-I, resulting in induction of a class I MHC transactivator, NLRC5, and subsequent upregulation of MHC-I.
Pubmed
25972545
Section of the abstract supporting the evidence
IMPORTANCE
Number of the section of the abstract supporting the evidence
2
Number of the sentence supporting the evidence
12
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00081432561624091
Drugs