Annotation Detail

Information
Associated Genes
APC
Associated Variants
APC p.Ile1307Lys (p.I1307K) ( ENST00000257430.9, ENST00000504915.3, ENST00000507379.6, ENST00000508376.6, ENST00000509732.6, ENST00000512211.7, ENST00000713638.1, ENST00000713639.1 )
APC p.Ile1307Lys (p.I1307K) ( ENST00000257430.9, ENST00000504915.3, ENST00000507379.6, ENST00000508376.6, ENST00000509732.6, ENST00000512211.7, ENST00000713638.1, ENST00000713639.1 )
Associated Disease
polyps
Source Database
DisGeNET
Description
APC I1307K increases risk of transition from polyp to colorectal carcinoma in Ashkenazi Jews.
Pubmed
11159880
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.022016586203497
Year of publication
2001
Drugs