Annotation Detail

Information
Associated Genes
APC
Associated Variants
APC p.Glu1317Gln (p.E1317Q) ( ENST00000257430.9, ENST00000504915.3, ENST00000507379.6, ENST00000508376.6, ENST00000509732.6, ENST00000512211.7, ENST00000713638.1, ENST00000713639.1 )
APC p.Glu1317Gln (p.E1317Q) ( ENST00000257430.9, ENST00000504915.3, ENST00000507379.6, ENST00000508376.6, ENST00000509732.6, ENST00000512211.7, ENST00000713638.1, ENST00000713639.1 )
Associated Disease
adenoma
Source Database
DisGeNET
Description
In the present study, 608 cases (377 patients with CRC, 145 patients with 4-100 lifetime adenomas, and 86 with < or =3 lifetime adenomas), and 679 controls (362 spouses and 317 patients with normal colonoscopy) were screened for the APC E1317Q variant.
Pubmed
14578138
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.190731621915964
Year of publication
2003
Drugs