Annotation Detail
Information
- Associated Genes
- RIGI
- Associated Variants
-
RIGI MUTATION
RIGI MUTATION - Associated Disease
- RNA Virus Infections
- Source Database
- DisGeNET
- Description
- A novel, sequence-dependent, uridine-rich RIG-I agonist generated a protective antiviral response in vitro and in vivo and was effective at concentrations 100-fold lower than prototype sequences or other RNA agonists, highlighting the robust activity and potential clinical use of the 5'pppRNA against RNA virus infection.
- Pubmed
- 26018150
- Section of the abstract supporting the evidence
- IMPORTANCE
- Number of the section of the abstract supporting the evidence
- 2
- Number of the sentence supporting the evidence
- 11
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00190009310456212
Drugs