Annotation Detail
Information
- Associated Genes
- TIMP1
- Associated Variants
-
TIMP1 MUTATION
TIMP1 MUTATION - Associated Disease
- Cerebrovascular accident
- Source Database
- DisGeNET
- Description
- Our results provide evidence for a positive effect of simvastatin on the MMP metabolism in human BMECs and experimental stroke mainly by means of the increased expression and secretion of TIMP-1 and TIMP-2.
- Pubmed
- 25476155
- Section of the abstract supporting the evidence
- ALL_TEXT_3/3
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 8
- Original source reporting the Gene Disease association
- BeFree,RGD
- DisGENET score for the Gene Disease association
- 0.0802714418720803
Drugs