Annotation Detail

Information
Associated Genes
FOXA1
Associated Variants
FOXA1 MUTATION
FOXA1 MUTATION
Associated Disease
Tumor Progression
Source Database
DisGeNET
Description
Furthermore, MT1DP was revealed as a negative regulator of Alfa-fetoprotein (AFP), a classic liver cancer tumor marker, through inhibiting protein synthesis of Forkhead box A1 (FoxA1), an important transcription factor in liver development and cancer progression.
Pubmed
25261601
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
7
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000542883744160607
Drugs