Annotation Detail

Information
Associated Genes
VEGFA
Associated Variants
PLA2G12A p.Glu115= (p.E115=), ENSG00000285330 p.Glu557= (p.E557=) ( ENST00000243501.10, ENST00000502283.1 )
PLA2G12A p.Glu115= (p.E115=), ENSG00000285330 p.Glu557= (p.E557=) ( ENST00000243501.10, ENST00000502283.1 )
Associated Disease
Exudative age-related macular degeneration
Source Database
DisGeNET
Description
Suggestive association between PLA2G12A single nucleotide polymorphism rs2285714 and response to anti-vascular endothelial growth factor therapy in patients with exudative age-related macular degeneration.
Pubmed
23112570
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00624316305784698
Year of publication
2012
Drugs