Annotation Detail
Information
- Associated Genes
- PTPN22
- Associated Variants
-
LACC1 p.Ile254Val (p.I254V)
(
ENST00000325686.7,
ENST00000441843.5 )
PTPN22 p.Trp620Arg (p.W620R) ( ENST00000525799.1, ENST00000538253.5, ENST00000420377.6, ENST00000528414.5, ENST00000460620.5, ENST00000359785.10 )
LACC1 p.Ile254Val (p.I254V) ( ENST00000325686.7, ENST00000441843.5 )
PTPN22 p.Trp620Arg (p.W620R) ( ENST00000359785.10, ENST00000420377.6, ENST00000460620.5, ENST00000525799.1, ENST00000528414.5, ENST00000538253.5 ) - Associated Disease
- ulcerative colitis
- Source Database
- DisGeNET
- Description
- SNP-SNP interaction analyses showed that the combination of SNPs in the PTPN22 (rs2476601) and C13orf31 (rs3764147) genes increase the risk for UC.
- Pubmed
- 23974994
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00900118904036822
- Year of publication
- 2014
Drugs