Annotation Detail

Information
Associated Genes
FGFR1
Associated Variants
FGFR1 MUTATION
FGFR1 MUTATION
Associated Disease
Malignant neoplasm of lung
Source Database
DisGeNET
Description
FGFR1 activation is an escape mechanism in human lung cancer cells resistant to afatinib, a pan-EGFR family kinase inhibitor.
Pubmed
25115383
Section of the abstract supporting the evidence
TITLE
Number of the section of the abstract supporting the evidence
0
Number of the sentence supporting the evidence
0
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00380018620912425
Drugs