Annotation Detail

Information
Associated Genes
MSH2
Associated Variants
MSH2 p.His639Tyr (p.H639Y) ( ENST00000406134.5, ENST00000543555.6, ENST00000233146.7, ENST00000645506.1, ENST00000713854.1, ENST00000713919.1 )
MSH2 p.His639Tyr (p.H639Y) ( ENST00000233146.7, ENST00000406134.5, ENST00000543555.6, ENST00000645506.1, ENST00000713854.1, ENST00000713919.1 )
Associated Disease
Colorectal cancer, hereditary nonpolyposis, type 1
Source Database
DisGeNET
Description
Functional analysis of human MLH1 and MSH2 missense variants and hybrid human-yeast MLH1 proteins in Saccharomyces cerevisiae.
Pubmed
11555625
Original source reporting the Gene Disease association
UNIPROT
DisGENET score for the Gene Disease association
0.32
Year of publication
2001
Drugs