Annotation Detail

Information
Associated Genes
CYP11B1
Associated Variants
CYP11B1 p.Arg448His (p.R448H) ( ENST00000292427.10, ENST00000377675.3, ENST00000517471.5 )
CYP11B1 p.Arg43Gln (p.R43Q) ( ENST00000292427.10, ENST00000377675.3, ENST00000517471.5 )
CYP11B1 p.Arg448His (p.R448H) ( ENST00000292427.10, ENST00000377675.3, ENST00000517471.5 )
CYP11B1 p.Arg43Gln (p.R43Q) ( ENST00000292427.10, ENST00000377675.3, ENST00000517471.5 )
Associated Disease
Congenital adrenal hyperplasia due to 11-Beta-hydroxylase deficiency
Source Database
DisGeNET
Description
Functional consequences of seven novel mutations in the CYP11B1 gene: four mutations associated with nonclassic and three mutations causing classic 11{beta}-hydroxylase deficiency.
Pubmed
20089618
Original source reporting the Gene Disease association
UNIPROT
DisGENET score for the Gene Disease association
0.487871814290329
Year of publication
2010
Drugs