Annotation Detail

Information
Associated Genes
ACVRL1
Associated Variants
ACVRL1 MUTATION
ACVRL1 MUTATION
ACVRL1 p.Gly211Asp (p.G211D) ( ENST00000713619.1, ENST00000552678.2, ENST00000547400.6, ENST00000551576.6, ENST00000419526.6, ENST00000388922.9, ENST00000550683.5 )
ACVRL1 p.Cys344Tyr (p.C344Y) ( ENST00000419526.6, ENST00000550683.5, ENST00000388922.9, ENST00000551576.6, ENST00000552678.2, ENST00000547400.6, ENST00000713619.1 )
ACVRL1 p.Gly211Asp (p.G211D) ( ENST00000388922.9, ENST00000419526.6, ENST00000547400.6, ENST00000550683.5, ENST00000551576.6, ENST00000552678.2, ENST00000713619.1 )
ACVRL1 p.Cys344Tyr (p.C344Y) ( ENST00000388922.9, ENST00000419526.6, ENST00000547400.6, ENST00000550683.5, ENST00000551576.6, ENST00000552678.2, ENST00000713619.1 )
Associated Disease
OSLER-RENDU-WEBER SYNDROME 2
Source Database
DisGeNET
Description
Molecular and functional analysis identifies ALK-1 as the predominant cause of pulmonary hypertension related to hereditary haemorrhagic telangiectasia.
Pubmed
14684682
Original source reporting the Gene Disease association
UNIPROT
DisGENET score for the Gene Disease association
0.44
Year of publication
2003
Drugs