Annotation Detail

Information
Associated Genes
KL
Associated Variants
KL MUTATION
KL MUTATION
Associated Disease
Papillary serous cystadenocarcinoma
Source Database
DisGeNET
Description
Klotho mRNA levels were reduced in 16 of 19 EOC cell lines and immunohistochemistry analysis revealed high expression in normal ovaries, and reduced expression in 100 of 241 high grade papillary-serous adenocarcinoma of the ovaries, fallopian tubes and peritoneum.
Pubmed
25827069
Section of the abstract supporting the evidence
ALL_TEXT_2/3
Number of the section of the abstract supporting the evidence
2
Number of the sentence supporting the evidence
4
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000271441872080303
Drugs