Annotation Detail

Information
Associated Genes
MIR146A
Associated Variants
rs2910164
rs2910164
Associated Disease
liver carcinoma
Source Database
DisGeNET
Description
A common G/C polymorphism (rs2910164) in the precursor (pre-) miR-146a gene engaged in NF-κB signaling and apoptosis pathways has been reported to modulate the genetic risk of hepatocellular carcinoma by increased G-allelic production of mature miR-146a.
Pubmed
22893469
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0105202196626753
Year of publication
2012
Drugs