Annotation Detail
Information
- Associated Genes
- CCND1
- Associated Variants
-
CCND1 MUTATION
CCND1 MUTATION - Associated Disease
- Proliferative retinopathy
- Source Database
- DisGeNET
- Description
- Since cyclin D1 is a key regulator of cell cycle G1/S phase progression essential for proliferation, these findings further strengthen the critical involvement of thrombin in the development of proliferative retinopathies and may provide pharmacologic targets for the prevention or treatment of these diseases.
- Pubmed
- 26247679
- Section of the abstract supporting the evidence
- ALL_TEXT_3/3
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 8
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000271441872080303
Drugs