Annotation Detail

Information
Associated Genes
FOXA1
Associated Variants
FOXA1 MUTATION
FOXA1 MUTATION
Associated Disease
Malignant neoplasm of prostate
Source Database
DisGeNET
Description
Taken together, our data illustrate the mechanistic details by which cooperativity and equilibrium with FOXA1 define AR cistrome and reveal a previously unknown function of FOXA1 in inhibiting AR signalling and castration-resistant prostate cancer growth.
Pubmed
24875621
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
7
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00570027931368637
Drugs