Annotation Detail

Information
Associated Genes
FOXA1
Associated Variants
FOXA1 MUTATION
FOXA1 MUTATION
Associated Disease
Malignant neoplasm of prostate
Source Database
DisGeNET
Description
In particular, we described the use of Epidaurus to (i) integrate epigenetic data from prostate cancer cell lines to validate the activation function of EZH2 in castration-resistant prostate cancer and to (ii) study the mechanism of androgen receptor (AR) binding deregulation induced by the knockdown of FOXA1.
Pubmed
25378314
Section of the abstract supporting the evidence
ALL_TEXT_2/3
Number of the section of the abstract supporting the evidence
2
Number of the sentence supporting the evidence
4
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00570027931368637
Drugs