Annotation Detail
Information
- Associated Genes
- SERPINE1
- Associated Variants
-
SERPINE1 MUTATION
SERPINE1 MUTATION - Associated Disease
- Myasthenia Gravis, Autoimmune, Experimental
- Source Database
- DisGeNET
- Description
- In an attempt to treat EAMG with an 18aa peptide derived from the PA system inhibitor (PAI-1), designed to tether out the endogenous inhibitor, a significant suppression of disease severity was demonstrated.
- Pubmed
- 24423642
- Section of the abstract supporting the evidence
- ALL_TEXT_2/3
- Number of the section of the abstract supporting the evidence
- 2
- Number of the sentence supporting the evidence
- 4
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000271441872080303
Drugs