Annotation Detail

Information
Associated Genes
ERCC2
Associated Variants
ERCC2 p.Arg683Trp (p.R683W) ( ENST00000391944.8, ENST00000391945.10, ENST00000684407.1 )
ERCC2 p.Arg683Trp (p.R683W) ( ENST00000391944.8, ENST00000391945.10, ENST00000684407.1 )
Associated Disease
Xeroderma Pigmentosum, Complementation Group D
Source Database
DisGeNET
Description
In fact, we demonstrate that the VDR transactivation defect resides in Ets1, another activator that cannot be phosphorylated by TFIIH in XP-D cells.
Pubmed
15494306
Original source reporting the Gene Disease association
UNIPROT
DisGENET score for the Gene Disease association
0.565428837441606
Year of publication
2004
Drugs