Annotation Detail

Information
Associated Genes
MSH6
Associated Variants
MSH6 MUTATION
MSH6 MUTATION
Associated Disease
Hereditary Nonpolyposis Colorectal Cancer
Source Database
DisGeNET
Description
Two MMR genes namely MLH1 and MSH2 account for majority of LS cases while MSH6 and PMS2 may account for a minor proportion.
Pubmed
25420488
Section of the abstract supporting the evidence
ALL_TEXT_1/3
Number of the section of the abstract supporting the evidence
1
Number of the sentence supporting the evidence
2
Original source reporting the Gene Disease association
BeFree,CLINVAR,GAD,ORPHANET
DisGENET score for the Gene Disease association
0.277111591604881
Drugs