Annotation Detail
Information
- Associated Genes
- PLAC8
- Associated Variants
-
PLAC8 MUTATION
PLAC8 MUTATION - Associated Disease
- pancreatic ductal adenocarcinoma
- Source Database
- DisGeNET
- Description
- Plac8 thus provides a mechanistic link between primary oncogenic mutations and the induction of autophagy, a central mechanism of metabolic reprogramming, during PDA progression.
- Pubmed
- 24794439
- Section of the abstract supporting the evidence
- ALL_TEXT_3/3
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 6
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000271441872080303
Drugs