Annotation Detail

Information
Associated Genes
ACVRL1
Associated Variants
ACVRL1 MUTATION
ACVRL1 MUTATION
Associated Disease
tumor vasculature
Source Database
DisGeNET
Description
Endoglin and ALK1 receptor levels in tumor vasculature correlate inversely with prognosis in humans, whereas in mice, endoglin deficiency decelerates tumor progression.
Pubmed
25279424
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
7
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000271441872080303
Drugs