Annotation Detail

Information
Associated Genes
MSH2
Associated Variants
MSH2 p.Ala636Pro (p.A636P) ( ENST00000233146.7, ENST00000406134.5, ENST00000543555.6, ENST00000645506.1, ENST00000713854.1, ENST00000713919.1 )
MSH2 p.Ala636Pro (p.A636P) ( ENST00000233146.7, ENST00000406134.5, ENST00000543555.6, ENST00000645506.1, ENST00000713854.1, ENST00000713919.1 )
Associated Disease
endometrial carcinoma
Source Database
DisGeNET
Description
High risk of colorectal and endometrial cancer in Ashkenazi families with the MSH2 A636P founder mutation.
Pubmed
21419771
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0306405939366718
Year of publication
2011
Drugs