Annotation Detail

Information
Associated Genes
PIK3CA
Associated Variants
PIK3CA MUTATION
PIK3CA MUTATION
Associated Disease
Congenital Lipomatous Overgrowth, Vascular Malformations, and Epidermal Nevi
Source Database
DisGeNET
Description
We detected a mosaic disease-causing mutation in PIK3CA by sequencing of DNA extracted from cultured amniotic cells, but not from DNA directly prepared from an amniotic fluid sample in a fetus with prenatally suspected CLOVES syndrome.
Pubmed
25044986
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
3
Original source reporting the Gene Disease association
BeFree,CLINVAR,ORPHANET,UNIPROT
DisGENET score for the Gene Disease association
0.360814325616241
Drugs