Annotation Detail

Information
Associated Genes
KRT10
Associated Variants
KRT10 MUTATION
KRT10 MUTATION
Associated Disease
Congenital reticular ichthyosiform erythroderma
Source Database
DisGeNET
Description
Because reversion is not observed with other disease-causing keratin mutations, the results of this study implicate KRT1 and KRT10 C-terminal frameshift mutations in the high frequency of revertant mosaicism in IWC.
Pubmed
25774499
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
8
Original source reporting the Gene Disease association
BeFree,CTD_human,ORPHANET
DisGENET score for the Gene Disease association
0.241085767488321
Drugs