Annotation Detail

Information
Associated Genes
HTRA2
Associated Variants
LOXL3 c.*908C>T, HTRA2 p.Gly399Ser (p.G399S) ( ENST00000258080.8, ENST00000352222.7, ENST00000437202.2, ENST00000696727.1, ENST00000264094.8, ENST00000409249.5 )
LOXL3 c.*908C>T, HTRA2 p.Gly399Ser (p.G399S) ( ENST00000258080.8, ENST00000352222.7, ENST00000437202.2, ENST00000696727.1, ENST00000264094.8, ENST00000409249.5 )
Associated Disease
Parkinson disease 13, autosomal dominant, susceptibility to
Source Database
DisGeNET
Description
Loss of function mutations in the gene encoding Omi/HtrA2 in Parkinson's disease.
Pubmed
15961413
Original source reporting the Gene Disease association
UNIPROT
DisGENET score for the Gene Disease association
0.44
Year of publication
2005
Drugs