Annotation Detail

Information
Associated Genes
COL11A1
Associated Variants
PLEKHA7 c.221+26931A>G ( ENST00000698836.1, ENST00000531066.6, ENST00000355661.7, ENST00000532079.1 )
COL11A1 p.Pro1323Leu (p.P1323L) ( ENST00000353414.8, ENST00000358392.6, ENST00000512756.5, ENST00000370096.9 )
rs1015213
PLEKHA7 c.221+26931A>G ( ENST00000355661.7, ENST00000531066.6, ENST00000532079.1, ENST00000698836.1 )
COL11A1 p.Pro1323Leu (p.P1323L) ( ENST00000353414.8, ENST00000358392.6, ENST00000370096.9, ENST00000512756.5 )
rs1015213
Associated Disease
primary angle-closure glaucoma
Source Database
DisGeNET
Description
Three loci defined by single nucleotide polymorphisms (SNPs) rs11024102 in PLEKHA7, rs3753841 in COL11A1, and rs1015213 between the PCMTD1 and ST18 genes, recently have been associated with primary angle closure glaucoma (PACG).
Pubmed
23847314
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00108576748832121
Year of publication
2013
Drugs