Annotation Detail

Information
Associated Genes
CAPN3
Associated Variants
CAPN3 p.Thr184ArgfsTer36 (p.T184Rfs*36) ( ENST00000397163.8, ENST00000349748.8, ENST00000318023.11, ENST00000357568.8 )
CAPN3 p.Thr184ArgfsTer36 (p.T184Rfs*36) ( ENST00000318023.11, ENST00000349748.8, ENST00000357568.8, ENST00000397163.8 )
Associated Disease
Muscular Dystrophies, Limb-Girdle
Source Database
DisGeNET
Description
The CAPN3 gene mutation c.550delA is rather frequently observed in German patients with LGMD2, but also occasionally in cases with isolated hyperCKemia.
Pubmed
17702496
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0359097792879131
Year of publication
2007
Drugs