Annotation Detail

Information
Associated Genes
DEFB1
Associated Variants
DEFB1 c.*87A>G ( ENST00000297439.4 )
DEFB1 c.-20G>A ( ENST00000297439.4 )
DEFB1 c.-44G>C ( ENST00000297439.4 )
DEFB1 c.*87A>G ( ENST00000297439.4 )
DEFB1 c.-20G>A ( ENST00000297439.4 )
DEFB1 c.-44G>C ( ENST00000297439.4 )
Associated Disease
leprosy
Source Database
DisGeNET
Description
A study was done on the association of three single nucleotide polymorphisms (SNPs) in the beta-defensin 1 gene (DEFB1) - 668 C/G (-44 C/G or rs1800972; in 5' UTR), 692 A/G (-20 A/G or rs11362; in 5' UTR) and A1836G (rs1800971; in 3' UTR) - with leprosy susceptibility per se and clinical leprosy variants.
Pubmed
19460328
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000271441872080303
Year of publication
2009
Drugs