Annotation Detail

Information
Associated Genes
Associated Variants
NM_000041.4(APOE):c.[388=;526=] AND APOE3 ISOFORM
NM_000041.4(APOE):c.[388=;526=] AND APOE3 ISOFORM
Source Database
GWAS Catalog
Description
Genetic determinants of statin-induced low-density lipoprotein cholesterol reduction: the Justification for the Use of Statins in Prevention: an Intervention Trial Evaluating Rosuvastatin (JUPITER) trial.
GWAS Catalog disease or trait
Response to statins (LDL cholesterol change)
GWAS Catalog p-Value
2E-47
GWAS Odds ratio OR beta coefficient
6.2
GWAS 95% confidence interval
[5.42-6.98] mg/dL decrease
GWAS parent term
Lipid or lipoprotein measurement
URL
http://www.ebi.ac.uk/efo/EFO_0007804
URL
http://www.ebi.ac.uk/efo/EFO_0004611
GWAS parent term
Response to drug
URL
http://purl.obolibrary.org/obo/GO_0036273
Drugs